The Boston Red Sox moved to their new ballpark at 4 Yawkey Way in 1912. Fenway Park was said to be named after the Fenway neighborhood, which was created by filling in marshlands (the fens) in the back bay. However, that explanation may be somewhat suspect as owner John Taylor's family also owned the Fenway Realty Company.
The Red Sox first game at Fenway Park was on April 20th, 1912 in an 11 inning 7-6 win against the New York Highlanders (who were renamed the Yankees the following year).
For Fenway Park's centenary, the building was designated as a National Historical Landmark. As of 2012, the Red Sox spring training facility, Jetblue Park in Fort Myers Florida is known as Fenway South as the facility has the exact same dimensions as the so called "Cathedral of Boston"